We are developing ultra-fast chemical screening methods, using high throughput technology, that will allow researchers to test large numbers of chemicals at once and zero in on those most likely to increase breast cancer risk.

Publications and Presentations

Cardona, B. and R.A. Rudel. 2021. Application of an in vitro assay to identify chemicals that increase estradiol and progesterone synthesis and are potential breast cancer risk factorsEnvironmental Health Perspectives. doi.org/10.1289/EHP8608

Article

Cardona, B. and R.A. Rudel. 2020. US EPA's regulatory pesticide evaluations need clearer guidelines for considering mammary gland tumors and other mammary gland effectsMolecular and Cellular Endocrinology.  doi.org/10.1016/j.mce.2020.110927

Article

Bessonneau, V., and R.A. Rudel. 2020. Mapping the Human Exposome to Uncover the Causes of Breast Cancer. International Journal of Environmental Research and Public Health. 17(1): 189. doi.org/10.3390/ijerph17010189

Article

Grashow, R.G., V.Y. De La Rosa, S.M. Watford, J.M. Ackerman, R.A. Rudel. 2018. BCScreen: A gene panel to test for breast carcinogenesis in chemical safety screening. Computational Toxicology. 5:16-24. doi.org/10.1016/j.comtox.2017.11.003.

Abstract

Rudel, R., Kripke M.L., and Yaswen, P. Predicting Toxicity: Silent Spring Institute's High-throughput Screens for Chemicals Related to Breast Cancer. Collaborative on Health and the Environment. November 12, 2015.

slides and recording

Pan, S., C. Yuan, A. Tagmount, R.A. Rudel, J.M. Ackerman, P. Yaswen, C.D. Vulpe, D.C. Leitman. 2015. Parabens and Human Epidermal Growth Factor Receptor Ligands Cross-Talk in Breast Cancer Cells. Environmental Health Perspectives, 124(5):563-569. doi:10.1289/ehp.1409200

Article

Schwarzman M.R., J.M. Ackerman, S.H. Dairkee, S.E. Fenton, D. Johnson, K.M. Navarro, G. Osborne, R.A. Rudel, G.M. Solomon, L. Zeise, S. Janssen. 2015. Screening for chemical contributions to breast cancer risk:  A case study for chemical safety evaluation. Environmental Health Perspectives, 123(12):1255-1264. doi:10.1289/ehp.1408337

Article